Separating latent and acute TB

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Separating latent and acute TB

In theory, immunodiagnosis should be able to discriminate between latent and acute TB, because the immunopathoogic nature of the disease means there must be significant differences in either the type and/or magnitude of immune response that develop. But so far we have not been able to pinpoint them. Our investigations of immune responses after infection suggest that in a substantial number of f...

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During the second half of the twentieth century, researchers have been focused on breaking down science into small pieces, and in doing so have learned that understanding the small pieces does not necessarily translate into a greater understanding of the whole. Systems biology has emerged as a way of understanding these systems in total, but requires scientists to work through complexity to arr...

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Immunological Diagnosis of Active and Latent TB

Immunological diagnosis of tuberculosis (TB) is based on the immune responses against Mycobacterium tuberculosis (MTB). Immunological diagnosis can detect both active and latent TB, and can detect not only pulmonary TB but also extra-pulmonary TB. Compared to conventional diagnosis, immunological diagnostic tests have eminent advantages. On the other hand, there are still some limitations. As i...

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QuantiFERON-TB Gold and Tuberculin Skin Test for the Diagnosis of Latent Tuberculosis Infection in Children

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ژورنال

عنوان ژورنال: BMC Proceedings

سال: 2010

ISSN: 1753-6561

DOI: 10.1186/1753-6561-4-s3-o8